Images

Participation on the 31th European Crystallographic Meeting

admin

  The 31st European Crystallographic Meeting, ECM31, of the European Crystallographic Association took place in the Palace of Exhibition and Congresses (PEC) in Oviedo, Asturias, from 22-27 August 2018. ECM31 was setting up an attractive programme covering the latest advances in crystallography and related sciences to attract young and senior scientists as well as companies and general public. Our group take part in the conference with two lectures and two posters and spent an unforgettable time in Oviedo, Spain. MS36-O5: Read More …

Polymorphism of a porous hydrogen bond assisted ionic organic framework

admin

Dániel Vajk Horváth, Tamás Holczbauer,* Laura Bereczki, Roberta Palkó, Nóra Veronika May, Tibor Soós and Petra Bombicz  CrystEngComm (2018), accepted for publication The polymorphism of a porous, non-covalently bonded ionic organic framework is reported. The framework is constructed by hydrogen bonding and anion⋯π interactions. In a solvatomorphic lattice, pyridine takes part in the framework formation. The role of molecular rigidity in framework construction is proven by analogous non-porous crystals, where polymorphism also appears. Full text

Strain-Driven Direct Cross-Aldol and -Ketol Reactions of Four-Membered Heterocyclic Ketones

admin

 Zoltán Dobi, Tamás Holczbauer, and Tibor Soós* Org. Lett., 2015, 17 (11), pp 2634–2637 Abstract Owing to the ring strain and α-heteroatom effect, the four-membered heterocyclic ketones can undergo direct cross-aldol and -ketol reactions without the need for preformed enol or “enolate-like” intermediates. Besides the organocatalyzed cross-ketol addition onto their highly active carbonyl group, their ability to act as a nucleophilic donor has also been explored. As a result, a number of discrete aldol adducts were synthesized and the distinct reactivities were successfully combined into Read More …

Vanadium(IV/V) complexes of Triapine and related thiosemicarbazones: Synthesis, solution equilibrium and bioactivity

admin

Kowol CR, Nagy NV, Jakusch T, Roller A, Heffeter P, Keppler BK, Enyedy ÉA Journal of Inorganic Biochemistry 152 (2015) 62–73 Abstract The stoichiometry and thermodynamic stability of vanadium(IV/V) complexes of Triapine and two related α(N)-heterocyclic thiosemicarbazones (TSCs) with potential antitumor activity have been determined by pH-potentiometry, EPR and 51V NMR spectroscopy in 30% (w/w) dimethyl sulfoxide/water solvent mixtures. In all cases, mono-ligand complexes in different protonation states were identified. Dimethylation of the terminal amino group resulted in the formation of Read More …