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Expanding the Pillararene Chemistry: Synthesis and Application of a 10 + 1 Functionalized Pillar[5]arene

08/09/201729/01/2019 admin

Márton Bojtár, András Simon, Petra Bombicz, and István Bitter Organic Letters (2017) 19 (17), 4528–4531 A novel functionality was introduced in the pillararene family by the Claisen rearrangement of monoallyl pillar[5]arene. This new key derivative can lead to the formation of a 10 + 1 functionalized derivative, a useful scaffold for further derivatization. Except for the previously known monodeprotection reaction, all steps proceed efficiently with high yields and easy separation. In addition, a solvent-responsive pseudo[1]rotaxane was synthesized based on this novel functionality. Read More …

Petra Bombicz is appointed to be the Editor-in-Chief of Crystallography Reviews from 1st January 2018.

09/08/201707/09/2017 admin

Crystallography Reviews publishes English language reviews on topics in crystallography and crystal growth, covering all theoretical and applied aspects of biological, chemical, industrial, mineralogical and physical crystallography. The intended readership is the crystallographic community at large, as well as scientists working in related fields of interest.

The group received an OTKA grant

09/08/201707/09/2017 admin

OTKA grant of the National Research, Development and Innovation Office – NKFIH Title: Basics of “crystal engineering”: supramolecular interactions, polymorphysm, temperature and pressure Principal Investigator: Petra Bombicz Participants: Tamás Holczbauer Nóra V. May Laura Nagyné Bereczki Dániel Fegyverneki Gyula Tamás Gál

Nóra V. May has been awarded the J. Bolyai Research Scholarship of the Hungarian Academy of Sciences

09/08/201710/08/2017 admin

The aim of the J. Bolyai Research Scholarship is to cater for young researchers the possibility of realizing their research programs. The proposal of Nóra V. May, titled “Structural investigation of bioactive compounds by means of single crystal X-ray diffraction and electron paramagnetic resonance spectroscopy”, have been accepted.

The way from isostructurality to polymorphy. Where are the borders? The role of supramolecular interactions and crystal symmetries.

01/08/201729/01/2019 admin

Petra Bombicz Crystallography Reviews, 23(2), 118-151, 2017. ABSTRACT To produce substances with required physico-chemical properties demands the recognition of structural features of materials. It includes polymorphism and isostructurality which are strongly related with intermolecular interactions and crystal symmetries. Fine tuning of structural properties can be achieved by the application of substituents or in the case of multi-component systems by the introduction of molecules of different sizes, shapes and chemical compositions. How far can a crystal structure tolerate small molecular changes? Read More …

Exploring the boundaries of direct detection and characterization of labile isomers – a case study of copper(II)–dipeptide systems

10/07/201729/01/2019 admin

Eszter Tóth, Nóra V. May, Antal Rockenbauer, Gábor Peintler and Béla Gyurcsik Dalton Trans., 2017,46, 8157-8166 ABSTRACT The investigation of the linkage isomers of biologically essential and kinetically labile metal complexes in aqueous solutions poses a challenge, as these microspecies cannot be separately studied. Therefore, derivatives are commonly used to initially determine the stability or spectral characteristics of at least one of the isomers. Here we directly detect the isomers, describe the metal ion coordination sphere, speciation and thermodynamic parameters by Read More …

Ivan Bernal and Roger Lalancette visited our laboratory

09/06/201708/09/2017 admin

Prof Ivan Bernal from Houston University and Prof Roger Lalancette from Rudgers University, USA visited our laboratories on 9 June 2017. (Nóra V. May, Petra Bombicz, Roger Lalancette, Laura Nagyné Bereczki, Susan A. Bourne, Ivan Bernal)

Susan A. Bourne visited our laboratory

09/06/201711/08/2017 admin

Prof. Susan A Bourne, the Head of Chemistry Department, the University of Cape Town, South Africa visited us between 7 and 12 June 2017 and delivered a lecture on Chromophoric framework solids for sensing and storage. Chromophoric framework solids for sensing and storage Susan A. Bourne Centre for Supramolecular Chemistry Research, Department of Chemistry, University of Cape Town Abstract Polymeric coordination compounds, and their subset metal-organic frameworks (MOFs) have provided a rich source of interest to researchers in Read More …

Petra Bombicz is in the Programme Committee of the triennial IUCr Congress

09/02/201707/09/2017 admin

The congress will be held in Hyderabad, India in 2017. Petra Bombicz is the member of the European Chemical Crystallography group. https://www.iucr2017.org/

Structural, analytical and DSC references to resolution of 2-Methoxy-2-phenylacetic Acid with Chiral 1-Cyclohexylethylamines through Gas-Antisolvent Precipitation

11/12/201606/09/2017 admin

Amit D. Zodge, Petra Bombicz, Edit Székely, György Pokol, János Madarász Thermochimica Acta, 648, 23-31, (2017) ABSTRACT The system of intermolecular interactions is very similar in the solid state of the chiral and racemic α-methoxyphenylacetic acids (α-MPAA) indicated by both Differential Scanning Calorimetry (DSC)and FTIR-spectroscopy, and even proved by single crystal structure determination. It makes the resolution of such a racemate compound challenging even by supercritical fluid xtraction. The chiral(S)-α-methoxyphenylacetic acid (1) crystallizes in orthorhombic crystal system (space group P212121,a Read More …